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Article

The transcriptomic landscape of elderly acute myeloid leukemia identifies B7H3 and BANP as a favorable signature in high-risk patients

Publicated to:Frontiers In Oncology. 12 1054458-1054458 - 2022-11-24 12(), DOI: 10.3389/fonc.2022.1054458

Authors: Villar, S; Ariceta, B; Agirre, X; Urribarri, AD; Ayala, R; Martínez-Cuadrón, D; Bergua, JM; Vives, S; Algarra, L; Tormo, M; Martínez, P; Serrano, J; Simoes, C; Herrera, P; Calasanz, MJ; Alfonso-Piérola, A; Paiva, B; Martínez-López, J; San Miguel, JF; Prósper, F; Montesinos, P

Affiliations

CIBERONC Ctr Invest Biomed Red Canc, Pamplona, Spain - Author
Fdn Miguel Servet, Navarrabiomed, Pamplona, Spain - Author
Hosp Gen Albacete, Albacete, Spain - Author
Hosp San Pedro Alcantara, Caceres, Spain - Author
Hosp Univ & Politecn La Fe, Valencia, Spain - Author
Hosp Univ 12 Octubre, Madrid, Spain - Author
Hosp Univ Ramon y Cajal, Madrid, Spain - Author
Hosp Univ Reina Sofia, Inst Maimonides Invest Biomed Cordoba IMIBIC, Cordoba, Spain - Author
ICO Badalona Hosp Germans Trias & Pujol, Badalona, Spain - Author
Inst Invest Sanitaria Navarra IDISNA, Clin Univ Navarra, Serv Hematol & Terapia Celular, Pamplona, Spain - Author
Univ Navarra, CIMA, Program Hematol Oncol, Pamplona, Spain - Author
Univ Navarra, Ctr Invest Med Aplicada CIMA Lab Diagnost, Pamplona, Spain - Author
Univ Valencia, Hosp Clin, Valencia, Spain - Author
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Abstract

Keywords

activationb7-h3biomarkersclassificationelderlyexpressionp53prognosisprogressionsmar1transcriptomicsAcute myeloid leukemiaRna-seq

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Frontiers In Oncology due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2022, it was in position 85/241, thus managing to position itself as a Q2 (Segundo Cuartil), in the category Oncology. Notably, the journal is positioned en el Cuartil Q2 para la agencia Scopus (SJR) en la categoría Oncology.

From a relative perspective, and based on the normalized impact indicator calculated from the Field Citation Ratio (FCR) of the Dimensions source, it yields a value of: 2.22, which indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: Dimensions Jun 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-06-24, the following number of citations:

  • WoS: 4
  • Scopus: 5
  • Europe PMC: 1
  • OpenCitations: 3

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-06-24:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 4.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 4 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.