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This research was funded by the Instituto de Salud Carlos III through the grants CP15/00100 and PI18/00191 (Co-funded by the European Regional Development Fund. ERDF, a way to build Europe); and by La Marato de TV3 (project 201943-30). We thank CERCA Program/Generalitat de Catalunya for institutional support. LR-B, MF-N and RZ-R would like to thank the program were supported by the PFIS (FI20/00006), Sara Borrell (CD20/00036) and the Miguel Servet (CPII20/00009) programs from the Institute of Health Carlos III (Co-funded by the European Social Fund (ESF)-ESF investing in your future), respectively.

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Lignan exposure: a worldwide perspective

Publicat a:European Journal Of Nutrition. 61 (3): 1143-1165 - 2022-04-01 61(3), DOI: 10.1007/s00394-021-02736-4

Autors: Rizzolo-Brime, L; Caro-Garcia, EM; Alegre-Miranda, CA; Felez-Nobrega, M; Zamora-Ros, R

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Resum

Dietary lignans are phytoestrogens that are mostly found in plant-based foods, especially whole grains, seeds, nuts, legumes and vegetables. An accurate assessment of lignan exposure is crucial to evaluate their potential health benefits and to establish future recommendations and dietary guidelines. This narrative review aimed to (i) summarize the pros and the cons of the current main assessment methods for lignan exposurei.e., dietary questionnaires, food composition tables and biomarkers, (ii) describe the individual lignans more consumed from a worldwide perspective, as well as their main food sources, (iii) determine the lignans concentrations in both urine and blood, and explore their heterogeneity among countries, and finally (iv) discuss the main determinants of lignan exposure.

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