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Article

Bruton tyrosine kinase covalent inhibition shapes the immune microenvironment in chronic lymphocytic leukemia.

Publicated to:Haematologica. - 2025-03-13 (), DOI: 10.3324/haematol.2024.286663

Authors: Medina-Gil D; Palomo L; Navarro V; Lázaro G; Martín-Mur B; Hernández C; Castells O; Sánchez B; Muñoz-Torres PM; Pagès C; Pujadas G; Esteve-Codina A; Cabirta A; Ferrà C; Alcoceba M; Terol MJ; Andreu R; Martí M; Abrisqueta P; Bosch F; Crespo M;

Affiliations

- Author
Bioinformatic Unit, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona. - Author
CNAG-CRG, Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona. - Author
Department of Hematology, Cancer Research Institute of Salamanca, University Hospital of Salamanca, Salamanca. - Author
Department of Hematology, Hospital Clínico Universitario de Valencia, Valencia. - Author
Department of Hematology, Hospital Universitario Politécnico "La Fe", Valencia. - Author
Department of Hematology, Institut Català d'Oncologia - Hospital Germans Trias i Pujol, Josep Carreras Research Institute, Badalona. - Author
Department of Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain; Servei d'Hematologia, Vall d'Hebron Hospital Universitari, Experimental Hematology, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelon - Author
Experimental Hematology, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain; Department of Medicine, Universitat Autònoma de Barcelona, Bellaterra. - Author
Experimental Hematology, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain; Department of Medicine, Universitat Autònoma de Barcelona, Bellaterra. macrespo@vhio.net. - Author
Immunology Unit, Department of Cell Biology, Physiology and Immunology, Institut de Biotecnologia i Biomedicina (IBB), Universitat Autònoma de Barcelona, Bellaterra. - Author
Oncology Data Science (ODysSey) Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona. - Author
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Abstract

Keywords
Good health and well-being

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Haematologica due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2025, it was in position 11/97, thus managing to position itself as a Q1 (Primer Cuartil), in the category Hematology.

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-05-14:

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 0.5.
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
Continuing with the social impact of the work, it is important to emphasize that, due to its content, it can be assigned to the area of interest of ODS 3 - Good Health and Well-Being, with a probability of 51% according to the mBERT algorithm developed by Aurora University.